Weight-loss drug semaglutide does not slow Alzheimer's disease, two clinical trials find

Oral semaglutide (a GLP-1 pill) is not effective at slowing progression in patients with mild Alzheimer's disease, finds the ...
CIDRAP

Vitamin D supplements don’t cut COVID health care use, symptom severity, trial shows

While a randomized controlled trial of vitamin D 3 supplementation in COVID-19 patients didn’t yield a significant reduction ...

Observational analyses can complement randomized clinical trial findings for the study of HPV vaccine effectiveness

Led by researchers at NDORMS as part of the Data Analysis and Real World Interrogation Network (DARWIN EU) initiative, a new ...
Targeted Oncology

Post-HSCT Gilteritinib May Improve Outcomes in R/R FLT3-Mutated AML

Pooled evidence from 2 randomized trials and 6 observational cohorts suggests posttransplant gilteritinib maintenance may ...
The New England Journal of Medicine

Prehospital Whole Blood in Traumatic Hemorrhage — a Randomized Controlled Trial

Whole-blood transfusion has recently gained favor in the management of severe hemorrhage; however, data from large clinical trials evaluating its clinical effectiveness and safety are lacking. We ...
News-Medical.Net

GLP-1 drugs cut heart and kidney risks in type 1 diabetes study

In a large target trial emulation of 174,678 people with type 1 diabetes, GLP-1 receptor agonist initiation was associated ...