Cells rely on tiny molecules called microRNAs to tune which genes are active and when. Cells must carefully control the ...

An innovative CRISPR-Cas12f-based activator system may hold significant potential in the future of gene therapy and biological research, suggest researchers of a new study. The study highlights the ...

Researchers identified DHX29 as a key protein that detects non-optimal codons and represses inefficient mRNAs, revealing how ...

Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...

A newly identified cellular system monitors subtle variations in genetic coding, hinting at a hidden level of control over ...

The expression of genes has to be carefully regulated in cells; active genes give cells their identity and ability to function. Epigenetic features are just one way that cells control gene expression, ...

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...

A new study shows cells use dual RNA signals to control microRNA lifespan. This selective process protects gene regulation ...

Our circadian clocks play a crucial role in our health and well-being, keeping our 24-hour biological cycles in sync with light and dark exposure. Disruptions in the rhythms of these clocks, as with ...

Researchers identify a gene expression program in the living human brain that tracks with real-time neurotransmission, ...