Despite this, relatively little is known about the role of c-Rel or other NF-κB subunits in c-Myc-driven lymphomas. However, a recent study of Myc-driven B-cell lymphoma in mice revealed a tumour ...
The human c-rel proto-oncogene (REL) encodes a nuclear factor (NF)-κB family transcription factor. Misregulated REL is associated with B-cell malignancies in several ways (Gilmore et al., 2004).
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