More than 200 metabolic enzymes, many of which are normally tasked with producing energy in the mitochondria, are also found sitting directly on top of human DNA, according to a study published in ...

Scientists discovered hundreds of energy-making enzymes secretly working on human DNA—revealing a hidden “mini-metabolism” ...

An entirely new approach to inhibiting DNA-cleaving enzymes works through the aggregation of an otherwise non-toxic molecule. This discovery may lead to a much-needed method for curbing Streptococcus ...

If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by researchers at Goethe University Frankfurt, part of the Rhine-Main University ...

Deep in your muscles, an enzyme called AMPD1 helps turn chemical fuel into usable energy. When it does not work well, muscles tire faster.

A new family of enzymes enables precise cuts in single-stranded DNA, offering powerful new tools for genetic engineering and expanding possibilities in biotechnology. (Nanowerk News) A few years ago, ...

Researchers studying a DNA-cutting enzyme with a crucial role in regulating the structure of genes have discovered a broad role for its cutting activity in driving abnormal genetic rearrangements ...

Genome editing-based therapies typically aim to treat disease by correcting underlying genetic mutations in patient’s cells. However, most genetic disorders are caused by dozens or even thousands of ...

(Nanowerk Spotlight) Genetic engineering has brought us revolutionary advances in medicine, biotechnology, and our understanding of life itself. However, the precise manipulation of DNA sequences has ...

Frances Arnold's game-changing technique of "directed evolution" creates enzymes with unusual capabilities. Her own evolution made it possible.

Clumps of Mn007, which is a non-cytotoxic molecule, can inhibit DNA-cleaving enzymes specifically. “We believe that molecular aggregation will provide a rational approach for the discovery and ...